The main purpose of this article is to examine the elements of the crises and challenges of South-North Korean cooperation after the sixth nuclear test in North Korea in 2017, and to consider the possibility of South-North Korean cooperation concerning human security and the actual state of human security in North Korean in the sectors of welfare and food. Most importantly, the welfare and food sectors have become the most important issue of human security in North Korea due to the COVID-19 pandemic. These are directly connected to survival realistically accompanied by urgency and sensitivity. Welfare and food support are considered a field that can achieve cooperation without any great objection from North Korea in addition to international cooperation for humanitarian purposes. If these forms of South-North Korean cooperation become possible, they could become the trigger that opens the gate of communication in the South-North Korean relationship that is fixed with chronic welfare and food problems in North Korea and the relief of the economic sanctions in North Korea as prescribed by the UN and the US. The possibility of South-North Korean exchange through enhanced human security may be expanded to the relief of North Korean sanctions for the assurance of humanitarian activity, international cooperation and governance construction. At the same time, if South-North Korean cooperation is approached from a human security point of view, it may create momentum that results in the settlement of peace on the Korean Peninsula by acting as a catalyst that could relieve the problem of welfare and food faced by North Korea and transform the hardened South-North Korean relationship into a more conversational paradigm.