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[학위논문] 북한 폐결핵 환자에게서 분리된 결핵균의 전장유전체 분석 및 획득

...extensively <em>drug</em>-resistant (XDR) strains are of particular concern. To enhance the understanding of genomic features and resistance mechanisms of M. tuberculosis within this distinct epidemiological context, a two-part genomic investigation was conducted, employing high-fidelity long-read sequencing and comparative clinical genomics. Initially, a high-quality whole-genome reference sequence of a <em>drug</em>-susceptible...

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[학위논문] 북한 폐결핵 환자에게서 분리된 결핵균의 전장유전체 분석 및 획득

...extensively drug-resistant (XDR) strains are of particular concern. To enhance the understanding of genomic features and resistance mechanisms of M. tuberculosis within this distinct epidemiological context, a two-part genomic investigation was conducted, employing high-fidelity long-read sequencing and comparative clinical genomics. Initially, a high-quality whole-genome reference sequence of a drug-susceptible...

#Mycobacterium tuberculosis #Democratic People’s Republic of Korea #whole genome sequencing #drug susceptibility #genome evolution #drug acquisition

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